Depression is an interesting disease because a lot of people think that depression is just being sad. But sadness is just the tip of the iceberg. Depression is something they will deal with for the rest of their lives. About one in three of people in the US with depression have treatment resistant depression. There is new hope in the horizon, Ketamine. Known as a party drug and animal anesthetic, it is one of the newest legal forms of medication to treat depression. Infusion centers are popping up all over the country.